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Clinical Trials at Carolina Eyecare Physicians

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Clinical Studies in Carolina Eyecare Physicians
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Clinical Studies in South Carolina

At Carolina Eyecare Physicians, our commitment extends beyond patient care. Our team of ophthalmologists are actively involved in cutting-edge clinical research to advance the field of eye care.

We participate in ophthalmic and optometric studies to evaluate new treatments and technologies for a wide range of eye conditions. This dedication to research ensures our patients have access to the latest advancements and helps us provide the most effective vision care possible.

Visit us at one of our convenient locations across South Carolina!

Ongoing Clinical Trials

Cataract Surgery and Intraocular Lenses:

Evaluation of the Symfony with Optiblue Intraocular Lens Compared to The Vivity IOL Under Mesopic Conditions.         

Presbyopia correcting intraocular lenses (IOLs) are lenses designed to reduce the dependence on glasses after routine cataract surgery.  If you have healthy eyes and have been diagnosed with cataracts in both eyes, or, if you are experiencing the symptoms of cataracts including cloudy vision and difficulty driving at night, you may qualify for this study. The study evaluates two already FDA-approved IOLs that could reduce your dependence on glasses.

Compensation is available for qualifying patients.  Enrollment is limited.

Medicare & most insurance accepted.

Status: Active, enrolling 

Learn more

Evaluation and Clinical Outcomes After Routine Cataract Surgery with the Quatera® 700 and the Centurion® Vision System.   

If you have healthy eyes and have been diagnosed with cataracts in both eyes or are experiencing the symptoms of cataracts, including cloudy vision and difficulty driving at night, you may qualify for this study that evaluates two already FDA approved devices used to remove the cataract during surgery.

Compensation is available for qualifying patients.  Enrollment is limited.

Medicare & most insurance accepted.

Status: Active, enrolling

Learn more

RayOne EMV Toric IOL Clinical Study

If your doctor has informed you about the presence of cataracts and astigmatism, there is a

potential opportunity for you to take part in a clinical study focused on the EMV toric intraocular

lens (IOL) implant.

To qualify, you must:

– Be 22 years of age or older

– Have cataracts and astigmatism

– Meet all other study-related criteria

Participants receive:

– Thorough screening evaluation of your eye health

– Follow-up visits for up to 6 months

– Reimbursement for costs related to time and travel

HOW YOU CAN PARTICIPATE

Ask your eye doctor if you are a candidate for the EMV Toric IOL clinical study.

To learn more about the EMV Toric IOL clinical study, please contact the research team at (843) 380 2499

Caution: New Device—Limited by Federal (or United States) law to investigational use

Status: Active, not enrolling

Learn more

Clinical Investigation of the TECNIS® Next-Generation Intraocular Lens, Model DEN00V.             

Status: Active, not enrolling        

Learn more

RxSight: RxSight Light Adjustable Lens and Light Delivery Device New Enrollment Study.

Status: Active, enrollment closed

Learn more

Retina:

Efficacy, Safety, and Pharmacokinetics of the Port Delivery System with Ranibizumab in Participants with Diabetic Macular Edema Compared with Intravitreal Ranibizumab (Pagoda)

Status: Active, enrollment closed

Learn more

All clinical studies for Carolina Eyecare Physicians are conducted at the Mt. Pleasant location.

Hear From Our Patients

I wanted to express my heartfelt gratitude for the kindness and support I received during my participation in the research program. From the dedicated staff to every employee involved, your unwavering kindness and courtesy made a significant impact on me. It truly meant the world to me. I’m beyond thrilled with the results of the program. After relying on thick, unsightly glasses since fourth grade and later switching to contacts at sixteen, I can now see clearly without any aids. It’s a joy to watch my favorite TV shows and read my beloved books with just my pretty little reading glasses. I wish each of you a beautiful day, every day, and may you be blessed abundantly. Thank you for all you do, not just for me, but for all those whose lives you touch through your dedication and hard work.

“For years, I struggled with poor vision due to severe astigmatism. Wearing glasses became a part of my life at the young age of 8. I attempted to transition to contact lenses but could not get use to them. Then, when Dr. Solomon mentioned the possibility of participating in the research study, it felt like a beacon of hope. This chance to correct both my astigmatism and distance vision during cataract surgery was truly extraordinary, an opportunity I wouldn’t have had otherwise. Since undergoing the surgery, I’ve rediscovered the joy of activities I had reluctantly set aside due to my eyesight. But perhaps the most profound moment came immediately after the surgery when I caught sight of myself in the mirror. For the first time in over sixty years, I saw my face without glasses. It was an astonishing revelation, I never knew, and dare I say it, I realized I’m quite the good-looking fella. I am immensely grateful to Dr. Solomon and his research team who made this possible.”

“Taking part in the LASIK study was a game-changer for me. As a young person navigating the world with glasses, my vision struggles often felt like a barrier to fully experiencing life. I constantly worried about losing or breaking my glasses, or my contacts. When the opportunity came up to participate in the LASIK study, I saw it as a chance to break free from these limitations. The thought of waking up and being able to see clearly without reaching for glasses was incredibly appealing. Since undergoing LASIK as part of the study, my life has changed in ways I couldn’t have imagined. It’s liberating to go about my day without constantly adjusting or worrying about my vision. To anyone considering participating in a LASIK study or any vision research, I say go for it. It’s not just about improving your vision. it’s about reclaiming your freedom and embracing a new way of seeing the world.”

Past Clinical Trials

Dry Eyes

Pilot Study for Treatment of Meibomian Gland Dysfunction (MGD) Prior to Cataract Surgery.

Status: Completed

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A Prospective Randomized Masked Placebo Controlled Comparative Study to Measure the Effects of Omega-3 Fatty Acid Nutritional Supplementation on the Thickness of the Lipid Layer in Subjects Presenting with Dry Eye Symptoms Due to Meibomian Gland Dysfunction.

Status: Completed

 

Randomized Controlled Trial of Long-term Treatment Effectiveness for Meibomian Gland Dysfunction (MGD) and Evaporative Dry Eye.

Status: Completed

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Evaluating A Novel Strategy: The Synergy IOL Mixed and Matched with the Symfony with Intelilight.

Status: Completed

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Evaluation of Real-World Data on the Performance of the TECNIS Odyssey™ IOL.

Status: Completed

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Evaluation of Clareon Vivity/Vivity Toric.

Status: Completed

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Clareon toric vs Eyhance toric.

Status: Completed

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Evaluating the new Synergy IOL – First 3 months data from Two US centers.

Status: Completed

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Visual Performance and Patient Satisfaction with A New Monofocal Intraocular Lens.

Status: Completed

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Satisfaction and Spectacle Independence Evaluation of the Acrysof® IQ Vivity® Intraocular Lens Targeted for Emmetropia or Nanovision.

Status: Completed

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Clinical Comparison of Contrast Sensitivity Measures in the Pseudophakic Population.

Status: Completed

 

A Prospective Randomized Controlled Multi-Center Clinical Study to Evaluate the Safety and Effectiveness of The RxSight Light Adjustable Lens (LAL) In Subjects Desiring an Extended Depth of Focus

Status: Completed

 

Evaluation of Angle Kappa and Different Intraocular Lens Calculation Formulas in Acrysof® IQ Panoptix Intraocular Lens Outcomes, Visual Disturbances and Patient Satisfaction.

Status: Completed

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Clinical Investigation of the Safety and Effectiveness of an Investigational Model of the TECNIS® Intraocular Lens (BRAVO).

Status: Completed

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Clinical Investigation of the Tecnis Next Generation Intraocular Lenses.

Status: Completed

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Clinical Investigation of AcrySof® IQ PanOptix™ IOL Model TFNT00.

Status: Completed

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Post–Approval Study of the Tecnis® TORIC IOL Extended Cylinder Range (ECR), MODELS ZCT450, ZCT525 and ZCT600.

Status: Completed

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Postmarket Study of ORA With VerifEye+ and Barrett Toric Calculator Used for the Implantation of AcrySof Toric.

Status: Completed

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Optimizing the Assessment of Refractive Outcomes after Cataract Surgery and Implantation of a Monofocal IOL.

Status: Completed

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Study to Evaluate the Safety and Efficacy of KPI-121 1.0% Ophthalmic Suspension in Postsurgical Inflammation and Pain.

Status: Completed

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A Phase 3, Prospective, Randomized, Open Label, Parallel-design, Multicenter Study to Evaluate the Safety of IBI 10090 for the Treatment of Inflammation Associated with Cataract Surgery.

Status: Completed

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Clinical Evaluation of the Lenstec SBL-3™ Intraocular Lens.

Status: Completed

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Comparison of Dropless Prophylaxis after Routine Phacoemulsification to Standard Drops Regimen.

Status: Completed

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A Multi-Center, Prospective, Randomized, Contralateral Comparison of 1-Month Postoperative Refractive Outcomes between Intraoperative measurements obtained with the Optiwave Refractive Analysis System (ORA System®with VerifEye) Combined with Implantation of an Alcon Toric IOL and standard biometry and Alcon Toric IOL implantation.

Status: Completed

 

Clinical Outcomes Data Collection of Patients Who Are Undergoing Cataract Surgery with Alcon VERION.

Status: Completed

 

A Prospective Multi-Center Study to Evaluate Performance of Phacofragmentation with the LenSx laser.

Status: Completed

 

Intra-operative Metrics and Clinical Outcomes after Cataract Surgery with the Centurion Vision System and the Infiniti Vision System.

Status: Completed

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Clinical Investigation of AcrySof® IQ ReSTOR® Multifocal Toric Intraocular Lens Model SND1T2.

Status: Completed

 

A Study Evaluating the Surgical Procedure and Nomograms for Femtosecond Laser Created Arcuate Incisions in The Treatment Of Preexisting Astigmatism In Patients Scheduled To Undergo Monocular Cataract Surgery.

Status: Completed

 

Evaluation of a Modified Disposable Contact Lens Patient Interface for the LenSx laser in Cataract and Cornea Surgery.

Status: Completed

 

A Multicenter, Randomized, Controlled Study of the Safety and Effectiveness of ACRYSOF@ IQ ReSTOR@ +8.0 0 Multifocal IOL in Comparison to ACRYSOF IQ Monofocal IOL in Subjects with Age-Related Macular Degeneration and Cataract.

Status: Completed

 

A Prospective, Randomized, Contralateral, Multi-Center Trial to Evaluate The Safety And Efficacy Of Using The Alcon Lensx Femtosecond Laser In Cataract Surgery Compared To A Manual Group.

Status: Completed

 

Post Approval Study of the AcrySof® IQ Toric High Cylinder Power Intraocular Lens (IOL) Models SN6AT6-SN6AT9.

Status: Completed

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Evaluation of a Modified Disposable Contact Lens Patient Interface for the LenSx laser in Cataract and Cornea Surgery.

Status: Completed

 

Clinical Investigation of AcrySof® IQ ReSTOR® Multifocal Toric IOL Model SND1T3/ SND1T4/ SND1T5/ SND1T6.

Status: Completed

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Evaluation of the LenSx Laser System for Performing Anterior Capsulotomy, Phacofragmentation, and Corneal Arc Cuts/Incisions in Patients Undergoing Cataract Surgery for Removal of the Crystalline Lens.

Status: Completed

 

An Assessment of Residual Spherical Aberration, Postoperative Total High Order Aberrations and Functional Vision Correlation after SN60WF IOL Implantation.

Status: Completed

 

A Randomized subject-masked comparison of visual function after bilateral implantation of Presbyopia-correcting lenses.

Status: Completed

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An Assessment of Residual Spherical Aberration, Postoperative Total High Order Aberrations and Functional Vision Correlation after SN60WF IOL Implantation.

Status: Completed

 

A Randomized, Masked Multi-center Safety & Efficacy Study of the Effects of Preoperative & Postoperative Cataract Surgery Use of Difluprednate Ophthalmic Emulsion, 0.05% Compared to Prednisolone Acetate Ophthalmic Suspension 1% on Visual Acuity & Corneal Edema.

Status: Completed

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A Prospective, Randomized, Controlled, Single-Masked, Parallel Groups, Multicenter Clinical Investigation of the Glaukos Trabecular Micro-Bypass Stent Model GTS400 using the G2-M-IS Injector System in Conjunction with Cataract Surgery.

Status: Completed

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A Phase 2 Study Evaluating Safety and Efficacy of the Latanoprost Punctal Plug Delivery System (L-PPDS) in Subjects With Ocular Hypertension (OH) or Open Angle Glaucoma (OAG).

Status: Completed

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Clinical Investigation of the Glaukos® Trabecular Micro-Bypass Stent Model GTS400 in Conjunction with Cataract Surgery.

Status: Completed

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Pivotal Trial of WaveLight® EX500 Excimer Laser System for the Correction of Myopia with and without Astigmatism Using InnovEyes™ in Conjunction with InnovEyes™ sightmap.

Status: Completed

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A Clinical Study Evaluating the Safety, Efficacy and Patient Satisfaction In Regards To Visual Outcome In Eyes Where The Horizontal Corneal Flap Is Created With A Femtosecond Laser Using A 6×6 Spot Size Compare With Flaps Created With A 9×9 Spot Size, In Patients Who Are Undergoing A Bilateral Lasik Procedure.

Status: Completed

 

Visual outcomes and induction of high order aberrations after Myopic Wavefront-guided LASIK.

Status: Completed

 

Visual Outcomes and Induction of High Order Aberrations After Myopic Guided-Wavefront LASIK.

Status: Completed

 

A Clinical Study Evaluating the Safety, Efficacy and Patient Satisfaction on Corneal Sensation and Signs & Symptoms of Dry Eye, in Eyes Receiving A 30 Degree Side Cut Compared with Eyes Receiving a 140 Degree Side Cut in Creating the Horizontal Corneal Flap, in Individuals Who Are Undergoing a Bilateral Lasik Procedure.

Status: Completed

Ocriplasmin Research to Better Inform Treatment (ORBIT)

Status: Completed

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Surgeon Evaluation of the Optiwave® Refractive Analysis System with VerifEye+® (ORA System® with VerifEye+®).

Status: Completed

 

A Multi-Center, Prospective, Observer Masked, Clinical Evaluation of the Dynamic Reticle in the Optiwave Refractive Analysis System with VerifEye (ORA System® with VerifEye).

Status: Completed

 

A Multi-Center, Prospective, Evaluation of Images Captured on Aphakic Eyes utilizing an Orange® Optical Head with a Super Luminescent Diode Light Source (SLED).

Status: Completed

 

A Multi-Center, Prospective Evaluation of Aphakic IOL Power Calculation utilizing the ORange® Intraoperative Wavefront Aberrometer Performed in Eyes Undergoing Cataract Surgery or Refractive Lens Exchange which have undergone Previous LASIK or PRK.

Status: Completed

 

Refractive Outcomes Evaluation of the VERIONTM Image Guided System + ORA System with VerifEye.

Status: Completed

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A Device Evaluation Study to Assess the Physical and Clinical Performance of Prototype Punctal Plug Design Iterations.

Status: Completed

To find out more about clinical study opportunities with Carolina Eyecare Physicians please fill out the form below or contact us by phone or email.

Phone: (843) 380-2499

Email: cepresearch@cepmd.com

Clinical Studies Interest Form

Clinical Studies Interest

Integrity

We advocate and emulate high ethical conduct in all we do.

Leadership

We lead through example and mentoring. We strive to foster mutual respect and integrity, and recognize that compassion and competency must be the cornerstone of our professional interactions.

Lifelong Learning

We recognize lifelong learning is essential to our ability to continually develop and improve our staff, our practice, and our profession.

Excellence

We will focus on providing the highest level of patient service using a proactive, positive approach, and recognize that service excellence is best achieved when the members of an organization work together to successfully reach a common goal.

Locations

We have several convenient locations throughout South Carolina. Please view the nearest location to you or get directions below. 

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